abo blood groups distribution and cardiovascular major risk factors in healthy population

background : this study was designed to investigate whether there was an association between abo blood groups and car­diovascular risk factors in healthy population. methods : in this cross-sectional study, risk factors screening for cardiovascular disease(cvd) on 5000 healthy persons of go­lestan province, northern iran, in 2005 was estimated by a questionnaire that included age, sex, physical activity, smok­ing status, blood group type (if they had blood laboratory tests), weight, height, blood pressure and family history of coro­nary artery disease (cad). data were analyzed with spss version 11.5 and by using chi square and anova tests. a p-value less than 0.05 were considered as statistically significant. results : amongst 5000 subjects, 2920 had blood laboratory tests and their types of blood group were known. of the total of 2920, 57.4% were male, 70% were inactive, 14% were smoker, 25% were hypertensive, 23% obese, 21% had family history of cad and mean age was 41.52±12.317. blood group o(32.9%), a(30.1%), b(23.3%) and ab(13.7%), respectively had most frequency. amongst cardiac risk factors, only frequency of family history of cad in individual with different blood groups was different ( p < 0.01) and individual with a blood group reported more family history of cvd versus other blood groups. conclusion: amongst cardiovascular risk factors, only family history of cad had significant relation with abo.